The ginsenoside RH2 is derived from the dried root of the ginseng of the Araliaceae plant. It is suitable for patients with early cancer and immunocompromised to prevent tumorigenesis. Acute, severe, and advanced cancer patients, weak constitution, taking can improve autoimmune function, enhance anti-tumor ability, reduce side effects such as bone marrow suppression, peripheral blood changes, immunosuppression, nausea and vomiting, fatigue, hair loss, etc.; quality of life, extending life expectancy.
Ginsenosides Rh2 (GS-Rh2) is a protopanaxadiol type low sugar chain saponin monomer isolated from ginseng. It is a secondary ginsenoside produced by the decomposition of sugar chains on the ligand due to the thermal decomposition of some of the original ginseng diol group ginsenosides. Secondary ginsenosides, usually only by degradation, can be achieved.
Uses and benefits:
1. Regulating tumor cell signaling pathway system
The cell signaling pathway system refers to cells receiving external signals and transmitting extracellular signals into intracellular signals through a specific set of mechanisms, ultimately regulating specific gene expression and causing cellular responses.
2. Affecting cell telomerase activity
Telomerase is an RNA reverse transcriptase that reverse transcribes the important sequences of telomeres using its own RNA as a template. Telomerase is a specific marker of tumors. There is a saying that telomerase activity is high, tumor cells active Ginsenosides Rh2 inhibits telomerase activity so that the telomere length of tumor cells cannot be maintained and enters senescence and eventually dies.
3. Stop the synthesis and metabolism of essential elements of tumor cells
Ginsenosides Rh2 mainly exerts anti-tumor effect by blocking the synthesis and metabolism of some important enzymes in the biological reaction system. The treatment of malignant tumors according to this route is generally thorough and difficult to relapse.
4. Induce tumor cell apoptosis
Apoptosis, like flowering and falling, is an active physiological process. Under normal circumstances, there is always a dynamic balance between cell proliferation and apoptosis, which maintains the normal and stable proliferation of cells. When a certain factor causes the cell proliferation to be out of control and the apoptosis is blocked, it can cause abnormal proliferation of the cells and cause cancer. Studies have found that certain drugs can treat cancer or artificially accelerating cancer cell apoptosis.
5. Reversing the abnormal differentiation of tumor cells
Cell morphology is used to determine the degree of malignancy of cancer using the degree of cell differentiation to select a clinical treatment plan. It is generally believed that the degree of cell differentiation is high, the degree of malignancy is low, the degree of cell differentiation is low, and the degree of malignancy is high.
6. Reversing the drug resistance of cancer drugs
In the process of treating tumors, it is found that clinical chemotherapy failure is often associated with the resistance of tumor cells to chemotherapeutic drugs. Ginsenosides Rh2 can be used as a tumor resistance reversal agent to improve the antitumor activity of chemotherapeutic drugs. Ginsenoside has strong anti-tumor activity and can be used in the treatment of cancers resistant to anti-tumor various medicines.
7. To achieve anti-tumor purposes by improving immunity
Immune function is the barrier of its own natural defense disease. If the immune function is dysfunctional, the immune surveillance function will not be able to clear the mutant cells, which is one of the causes of tumors. Ginsenosides Rh2 can regulate and enhance the immune function of the body through various ways, and has a protective effect on the immune system.
8. Combining with chemotherapy drugs to increase efficiency and reduce toxicity
In the process of treating tumors, it is found that clinical chemotherapy failure is often associated with the resistance of tumor cells to chemotherapeutic drugs. Ginsenosides Rh2 can be used as a tumor resistance reversal agent to improve the antitumor activity of chemotherapeutic drugs. Generally, chemotherapeutic drugs are not easy to enter cancer cells. Ginsenosides Rh2 has hydrophilic and lipophilic properties and can easily enter the nucleus and kill cancer cells inside.